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Peer-Reviewed Publication
Heart Rhythm2026April 7, 2026Journal Article

Estimation of atrial fibrillation burden as a function of monitoring time without atrial fibrillation.

Linda S Johnson1, William F McIntyre2, Albin Edegran3, Jason G Andrade4, Alexander P Benz5, Taya Glotzer6, Jeffrey S Healey2, Emma Svennberg7
1Department of Clinical Sciences, Malmö, Lund University, Sweden; Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada. Electronic address: linda.johnson@med.lu.se.
2Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada; Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
3MEDICALgorithmics, Warsaw, Poland.
4Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
5Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada.
6Hackensack University Medical Center Hackensack, New Jersey; Hackensack Meridian School of Medicine, Nutley, New Jersey.
7Karolinska Institutet, Stockholm, Sweden; Department of Medicine Huddinge, Karolinska University Hospital, Stockholm, Sweden.

Abstract

BACKGROUND: Atrial fibrillation (AF) burden is associated with adverse outcomes; in some patients, very low AF burden may not be actionable. OBJECTIVE: This study aimed to model AF burden as a function of monitoring time without AF. METHODS: We included 11,639 US patients (median age 62 years [interquartile range 46‒73], 40.6% male) without permanent/persistent AF, monitored for ≥14 days in 2021…

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