A Pooled Blood Genome-Wide Association Study of Hypertension in Sindhi Families: Results from the DISFIN Study.

Samika Kanaskar¹, Ashwini A Patel², Manisha T Jaisinghani², Kanchan V Pipal², Mangesh Kanaskar³, Manju Mamtani^2,4, Hemant Kulkarni^2,4

¹Department of Public Health & Health Professions, University of Florida, Gainesville, FL 32611, USA.

²Lata Medical Research Foundation, Nagpur 440022, India.

³Precisely Software, Inc., Burlington, MA 01803, USA.

⁴M&H Research, LLC., San Antonio, TX 78249, USA.

PubMed PMC DOI PDF

Abstract

BACKGROUND: Hypertension is an important target for primordial prevention of complex, noncommunicable diseases, and its prevalence remains high across populations. The urban population in India is at a high risk of hypertension, but the genetic basis of hypertension in this population remains poorly understood. METHODS: We conducted a pooled whole-blood genome-wide association study of 28 pools r…

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