Rheumatic heart disease is not over: Cardiac cirrhosis and multivalvular sequelae in an endemic setting - A case series and review.

Yashendra Sethi¹, Narendra Dev Yadav², Saurabh Singhal³, Apoorv Pratap Singh⁴, Ankita Singh⁵, Shruti Agarwal⁶, Amit Sharma⁷, Chris Pavlovic⁸, Thomas Pavlovic⁹, Sameer Mehta¹⁰

¹Department of Medicine, Subharti Medical College, Swami Vivekanand Subharti University, Meerut, India; PearResearch, Dehradun, India; Vigyaved Healthcare, Dehradun, India; Lumen Foundation, Florida, US; Department of Cardiology, Subharti Medical College, Swami Vivekanand Subharti University, Meerut, India. Electronic address: yash@pearresearch.com.

²Department of Medicine, Subharti Medical College, Swami Vivekanand Subharti University, Meerut, India. Electronic address: narendradevyadav201292@gmail.com.

³Department of Medicine, Subharti Medical College, Swami Vivekanand Subharti University, Meerut, India. Electronic address: singhaldnb2007@yahoo.co.in.

⁴Department of Medicine, Subharti Medical College, Swami Vivekanand Subharti University, Meerut, India. Electronic address: apsjhs@gmail.com.

⁵Department of Medicine, Subharti Medical College, Swami Vivekanand Subharti University, Meerut, India. Electronic address: Singh18ankita10@gmail.com.

⁶Department of Medicine, Subharti Medical College, Swami Vivekanand Subharti University, Meerut, India. Electronic address: shrutiagarwalagra21@gmail.com.

⁷Department of Cardiology, Subharti Medical College, Swami Vivekanand Subharti University, Meerut, India. Electronic address: amit@pearresearch.com.

⁸Northshore Heart, Lutheran General Hospital, Chicago, IL, USA. Electronic address: chris@pearresearch.com.

⁹Northshore Heart, Lutheran General Hospital, Chicago, IL, USA. Electronic address: thomas@pearresearch.com.

¹⁰Lumen Foundation, Florida, US. Electronic address: sameer@pearresearch.com.

PubMed DOI

Abstract

BACKGROUND: Rheumatic Heart Disease (RHD) remains a major cause of valvular morbidity in endemic regions despite declining incidence in high-income countries. While early disease manifests as acute rheumatic fever, contemporary presentations increasingly reflect advanced structural sequelae. Congestive hepatopathy and cardiac cirrhosis secondary to chronic right-sided failure remain under-recogniz…

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