Febrile transfusion-associated circulatory overload in adult oncology patients.

Mayrin Correa Medina^1,2, Marisol Maldonado¹, Roland Bassett³, Fernando Martinez^1,4, Kimberly Klein¹, Colleen E Villamin¹, Adriana Knopfelmacher¹, Roman Gonta^1,2, James M Kelley^1,5

¹Division of Pathology and Laboratory Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

²Division of Pathology and Laboratory Medicine, Moffitt Cancer Center, Tampa, Florida, USA.

³Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

⁴Department of Pathology and Laboratory Medicine, University of Miami, Miller School of Medicine, Miami, Florida, USA.

⁵Pictor Labs, Los Angeles, California, USA.

PubMed DOI

Abstract

BACKGROUND AND OBJECTIVES: Transfusion-associated circulatory overload (TACO) is the leading cause of transfusion-related morbidity and mortality. We evaluated the incidence of TACO and its association with new fever (HOT-TACO) at a comprehensive cancer centre. MATERIALS AND METHODS: Retrospective review of haemovigilance data (July 2019-October 2020) identified 100 possible to definite TACO case…

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