Sex-related mortality differences in septic shock: A propensity score-matched study.

Stefano Fresilli¹, Rosa Labanca¹, Domenico Pontillo², Alessandro Belletti¹, Chiara Mariotti¹, Isatu Kargbo³, Francesca Rusconi⁴, Andrea Bruni⁵, Alberto Zangrillo⁶, Giovanni Landoni⁶,

¹Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.

²Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy. Electronic address: pontillo.domenico@hsr.it.

³TriNetX LLC, Cambridge, MA, USA.

⁴TriNetX Europe NV, Sint-Martens-Latem, Belgium.

⁵Department of Pharmacy, University of Calabria, Arcavacata di Rende, Italy.

⁶Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy; School of Medicine, Vita-Salute San Raffaele University, Milan, Italy.

PubMed DOI

Abstract

PURPOSE: This study aimed to evaluate sex-specific differences in 28-day mortality among young adults (18-55 years) with septic shock using a large propensity score-matched cohort. MATERIALS AND METHODS: We performed a retrospective propensity score-matched analysis using the TriNetX network. Adults 18-55 years old developing septic shock between January 2011 and January 2020 were identified. Wom…

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