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Peer-Reviewed Publication
JAMA Netw Open2026;9(3):e260983.March 2, 2026Journal Article

Prevalence and Size-Based Risk Categorization of Pancreatic Cysts Among Asymptomatic Individuals With Screening MRI.

Paul Wong1, Tommaso Pollini1, Sophia Hernandez1, Marco Zampese1, Letizia Todeschini1, Luis Laurean Aguilar1, Saqib Abdullah Basar2, Sam Hashemi2, Ajay V Maker1
1Division of Surgical Oncology, Department of Surgery, University of California, San Francisco, San Francisco.
2Prenuvo Inc, Vancouver, British Columbia, Canada.

Abstract

IMPORTANCE: Subsets of pancreatic cystic lesions (PCLs) are the only radiographically evident precursors to pancreatic cancer. Guidelines prioritize cyst size and high-risk features to determine the need for resection. However, the true prevalence of PCLs and risk factors for their development in the general population remain unknown, as available data are often biased by imaging performed in symp…

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