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NPJ Biol Timing Sleep2024;1(1)November 1, 2024Journal Article

Insomnia and its treatments-trend analysis and publication profile of randomized clinical trials.

Viviane Akemi Kakazu1, Marcia Assis2, Andrea Bacelar3, Andréia Gomes Bezerra1, Giovanna Lira Rosa Ciutti1, Silvia Gonçalves Conway4,5,6, José Carlos Fernandes Galduróz1, Luciano F Drager7, Mariana Pery Khoury1,8, Ingrid Porto Araújo Leite1, Ygor de Matos Luciano1, Dalva Poyares1,9, Sergio Tufik1,9, Gabriel Natan Pires10,11
1Departamento de Psicobiologia, Universidade Federal de São Paulo, São Paulo, Brasil.
2Clínica do Sono de Curitiba, Hospital São Lucas, Curitiba, Brasil.
3Clínica Bacelar - Neuro e Sono, Rio de Janeiro, RJ, Brasil.
4Instituto de Psiquiatria (IPq), Universidade de São Paulo, São Paulo, SP, Brasil.
5Departamento de Otoneurologia, Universidade de São Paulo, São Paulo, SP, Brasil.
6AkasA - Formação e Conhecimento, São Paulo, SP, Brasil.
7Unidades de Hipertensão, Instituto do Coração (InCor) e Disciplina de Nefrologia, Universidade de São Paulo, São Paulo, SP, Brasil.
8Faculdade de Medicina da Universidade Santo Amaro (UNISA), São Paulo, SP, Brasil.
9Instituto do Sono, São Paulo, SP, Brasil.
10Departamento de Psicobiologia, Universidade Federal de São Paulo, São Paulo, Brasil. gabriel.pires@unifesp.br.
11Instituto do Sono, São Paulo, SP, Brasil. gabriel.pires@unifesp.br.
PubMed PMC DOI PDF

Abstract

This study aimed to describe the publication profile of randomized controlled trials (RCTs) for insomnia. A systematic review of RCTs regarding interventions for non-comorbid insomnia in adults retrieved 132 RCTs: 58 related to pharmacological treatments, 71 to non-pharmacological treatments, and 3 to both interventions. The treatments with the biggest publication profile were digital CBT-I (dCBT-…

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