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Peer-Reviewed Publication
Eur J Pediatr2026;185(3)March 3, 2026Journal Article

Pediatricians' approaches to communicating side effects: a national survey.

Anna de Geus1,2,3, Dunya Seinen4, Marc A Benninga1, , Arine M Vlieger5
1Department of Pediatric Gastroenterology, Hepatology and Nutrition, Amsterdam University Medical Centre, Emma's Children Hospital, University of Amsterdam, Amsterdam, the Netherlands.
2Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
3Amsterdam Reproduction and Development Research Institute, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
4Department of Pediatrics, St. Antonius Hospital, Soestwetering 1, 3543 AZ, Utrecht, the Netherlands.
5Department of Pediatrics, St. Antonius Hospital, Soestwetering 1, 3543 AZ, Utrecht, the Netherlands. arine@vlieger.nl.
PubMed DOI

Abstract

UNLABELLED: Most parents and adolescents want comprehensive information about potential side effects (SE) of medication. However, such information can sometimes trigger side effects due to negative expectations: the so-called nocebo effect. To develop evidence-based strategies that meet information needs while minimizing nocebo effects, this study examined how pediatricians currently communicate a…

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