Health AI Central
Peer-Reviewed Publication
Ann Biomed Eng2026;54(9):3074-3087.September 1, 2026Journal Article

A Computational Framework for Simulating Patient-Specific TMJ Biomechanics Using a Combined Multibody Dynamics and Finite Element Approach.

Farhad Ahmadi1, Shuchun Sun1,2, Jichao Zhao1, Jian Chen1, Marshall B Wilson1, Brooke Damon1,2, Yongren Wu1,3, Konstantinia Almpani4, Rachel Chung4, Priyam Jani4, Peng Chen1,2, Elizabeth H Slate5, Janice S Lee4, Benedikt Sagl6,7, Hai Yao8,9
1Clemson-MUSC Joint Bioengineering Program, Department of Bioengineering, Clemson University, Clemson, SC, USA.
2Department of Oral Health Sciences, Medical University of South Carolina, Charleston, SC, USA.
3Department of Orthopaedics, Medical University of South Carolina, Charleston, SC, USA.
4Craniofacial Anomalies and Regeneration Section, National Institute of Dental and Craniofacial Research (NIDCR), NIH, Bethesda, MD, USA.
5Department of Statistics, Florida State University, Tallahassee, FL, USA.
6Competence Center Artificial Intelligence in Dentistry, University Clinic of Dentistry, Medical University of Vienna, Vienna, Austria. benedikt.sagl@meduniwien.ac.at.
7Comprehensive Center AI in Medicine, Medical University of Vienna, Vienna, Austria. benedikt.sagl@meduniwien.ac.at.
8Clemson-MUSC Joint Bioengineering Program, Department of Bioengineering, Clemson University, Clemson, SC, USA. haiyao@clemson.edu.
9Department of Oral Health Sciences, Medical University of South Carolina, Charleston, SC, USA. haiyao@clemson.edu.
PubMed PMC DOI PDF

Abstract

PURPOSE: Biomechanical parameters of the temporomandibular joint (TMJ), such as joint contact forces and intra-articular stresses, are suggested to contribute to the development of temporomandibular joint disorders, but are impractical to measure. In this study, we present a computational framework for evaluating these parameters by integrating a function assessment system and a patient-specific m…

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