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Peer-Reviewed Publication
J Med Econ2026;29(1):609-619.December 1, 2026Journal Article

Impact of offering blood-based testing alongside existing modalities for colorectal cancer screening among those who previously declined screening: an economic evaluation.

Shaun P Forbes1, Elifnur Yay Donderici1, Nicole Zhang1, Victoria M Raymond2, Amar K Das1, Peter S Liang3,4
1AI and Translational Medicine, Guardant Health Inc, Palo Alto, CA, USA.
2Screening Medical Affairs, Guardant Health Inc, Palo Alto, CA, USA.
3Division of Gastroenterology, NYU Grossman School of Medicine, New York, NY, USA.
4Department of Medicine, VA New York Harbor Health Care System, New York, NY, USA.

Abstract

AIM: Inadequate adherence to colorectal cancer screening reduces individual and population level health benefits. Blood-based tests offer a new modality that may help patients overcome barriers, but there are concerns about the impact of patients switching from existing guideline-recommended screening modalities. This study estimates the population health outcomes and cost-effectiveness of offerin…

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