Neuroimaging of acute myocardial injury in stroke: insights into brain lesion locations and network disconnections.

Petr Mikulenka¹, James W Garrard^2,3,4, Olivia N Murray^2,5, Alistair Perry², George Harston^2,4, Michal Mihalovič⁶, Petr Toušek⁶, Tomáš Peisker¹, Ivana Štětkářová¹, Davide Carone^2,3,4

¹Department of Neurology, Third Faculty of Medicine, Charles University and University Hospital Královské Vinohrady, Prague, Czechia.

²Brainomix Limited, Oxford, United Kingdom.

³Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.

⁴Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom.

⁵Division of Informatics, Imaging and Data Sciences, University of Manchester, Manchester, United Kingdom.

⁶Department of Cardiology, Third Faculty of Medicine, Charles University and University Hospital Královské Vinohrady, Prague, Czechia.

PubMed PMC DOI PDF

Abstract

INTRODUCTION: Acute myocardial injury (AMI) is frequently observed in patients with acute stroke and may be linked to lesion location within the central autonomic network (CAN). However, neuroimaging findings remain inconsistent, and the neuroanatomical basis remains unclear. We investigated associations between lesion location, structural disconnection, and AMI in acute stroke. METHODS: In this…

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