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Peer-Reviewed Publication
PeerJ2026;14e20826.January 1, 2026Journal Article

A double agent? Unveiling the chemical profile of the pathogenic fungus Pyrrhoderma noxium as an endophyte in true mangroves.

Ming Han Han1, Jing Sien Chang1, Jen-Kit Tan2, Swee Keong Yeap1, Wei Lun Ng1,3, Yoong Soon Yong1,4
1China-ASEAN College of Marine Sciences, Xiamen University Malaysia, Sepang, Selangor, Malaysia.
2Department of Biochemistry, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, Malaysia.
3College of Ocean and Earth Sciences, Xiamen University, Xiamen, China.
4R&D Quality Department, Osmosis Nutrition Sdn. Bhd., Nilai, Negeri Sembilan, Malaysia.

Abstract

Pyrrhoderma noxium, commonly referred to as the brown root rot pathogen, has previously been recognized as a pathogenic species. However, it has been largely overlooked for its capability to produce useful bioactive compounds. In this study, we report for the first time that the fungus has been isolated as an endophytic fungus (EF) from the leaves of true mangrove plant species, and chemically pro…

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