Physiologic Assessment Using Angiography-Derived Fractional Flow Reserve After Drug-Coated Balloon Angioplasty in De Novo Coronary Lesions.

Chun-Chin Chang^1,2,3, Jui-Yun Lee^1,2, Hsin Lin Chou³, Wei-Ting Sung^1,2, Ya-Wen Lu^2,3,4, Yi-Lin Tsai^1,2, Hsin-I Teng⁵, Ruey-Hsing Chou^1,2,3,6, Jean-Paul Aben⁷, Po-Hsun Huang^1,2,3

¹Department of Medicine, Division of Cardiology, Taipei Veterans General Hospital, Taipei, Taiwan.

²Cardiovascular Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan.

³Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.

⁴Department of Medicine, Division of Cardiology, Taichung Veterans General Hospital, Taichung, Taiwan.

⁵Heart Center, Cheng Hsin General Hospital, Taipei, Taiwan.

⁶Department of Critical Care Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.

⁷Pie Medical Imaging BV, Maastricht, the Netherlands.

PubMed DOI

Abstract

BACKGORUND: Drug-coated balloon (DCB) angioplasty offers a potential alternative to avoid permanent metallic stent implantation and the associated risk of in-stent restenosis. AIMS: This study aimed to evaluate the safety and effectiveness of DCB angioplasty for de novo coronary stenoses in real-world clinical practice. METHODS: This was a single-center, retrospective observational study. Betwee…

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Mentioned Companies

Pie Medical Imaging BV
affiliation

Other Funding

Cheng Hsin General Hospital
National Yang Ming Chiao Tung University Research Project(CY113-11206-04)

MeSH Terms

Humans0Fractional Flow Reserve, Myocardial*Angioplasty, Balloon, Coronary*Coronary Angiography*Treatment Outcome0Coated Materials, Biocompatible*Female0Retrospective Studies0Cardiac Catheters*Predictive Value of Tests0Male0Time Factors0Aged0Coronary Stenosis*Middle Aged0Coronary Artery Disease*Cardiovascular Agents*Risk Factors0

Keywords

coronary artery diseasedrug‐coated balloonpercutaneous coronary intervention

Article Info

PMID: 41732831
DOI: 10.1002/ccd.70527
Received: August 15, 2025
Accepted: February 19, 2026

How to Cite

Chang CC et al. Physiologic Assessment Using Angiography-Derived Fractional Flow Reserve After Drug-Coated Balloon Angioplasty in De Novo Coronary Lesions. Catheter Cardiovasc Interv2026;107(6):1701-1708. doi:10.1002/ccd.70527

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