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Peer-Reviewed Publication
Med Sci (Basel)2026;14(1)January 23, 2026Journal Article

Cardiovascular Complications of Seasonal Influenza in the Pre- and Post-COVID-19 Era: Epidemiology, Mechanisms, and Clinical Implications.

Chikodili Nora Nebuwa1, Chukwudi Kingsley Orjichukwu2, Rita Ogochukwu Orjichukwu3, Peter Kanayochukwu Akpunonu4, Paul Chikwado Ugwu5, Somtochukwu Godfrey Nnabuife6
1Nuvance Health, Vassar Brothers Medical Center, 45 Reade Place, Poughkeepsie, NY 12601, USA.
2Well Health Manitoba Clinic, 790 Sherbrook Street, Winnipeg, MB R3A 1M4, Canada.
3Medway Maritime Hospital, Gillingham ME7 5NY, UK.
4North London NHS Foundation Trust, IT Department, 3rd Floor, West Wing, St Pancras Hospital, 4 St Pancras Way, London NW1 0PE, UK.
5King George Hospital, Barley Lane, Ilford, Essex IG3 8YB, UK.
6University of Wolverhampton, Wulfruna Street, Wolverhampton, West Midlands WV1 1LY, UK.

Abstract

Influenza has long been a well-documented contributor to cardiovascular morbidity and mortality, particularly among high-risk groups. COVID-19 has notably altered the seasonality and natural history of pandemic influenza, with broad implications for related cardiac complications. This review examines the interaction between influenza and cardiovascular illness, especially myocardial infarction, co…

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