Peer-Reviewed Publication
Circ Popul Health Outcomes2026;19(4):e012216.April 1, 2026Journal Article

Association Between Life-Course Social and Racial Inequities and the Incidence of Major ECG Abnormalities in the ELSA-Brasil Cohort.

Alenice Aliane Fonseca1, Lidyane V Camelo1, Enrico Antônio Colosimo2, Marcelo M Pinto Filho3, Luisa C C Brant3,4, Jose Geraldo Mill5, Luana Giatti1, Sandhi Maria Barreto1,6, Antonio Luiz P Ribeiro1,3,4
1Postgraduate Program in Public Health, Department of Preventive and Social Medicine, School of Medicine, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil. (A.A.F., L.V.C., L.G., S.M.B., A.L.P.R.).
2Department of Statistics, Institute of Exact Sciences, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil (E.A.C.).
3Telehealth Center, Hospital das Clínicas/Empresa Brasileira de Serviços Hospitalares, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil (M.M.P.F., L.C.C.B., A.L.P.R.).
4Department of Internal Medicine, School of Medicine, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil (L.C.C.B., A.L.P.R.).
5Department of Physiological Sciences, Universidade Federal do Espírito Santo, Vitória, Brazil (J.G.M.).
6Hospital das Clínicas/Empresa Brasileira de Serviços Hospitalares, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil (S.M.B.).

Abstract

BACKGROUND: It remains unclear whether social determinants contribute to major ECG abnormalities (MEA), an early marker of cardiovascular disease, which predicts adverse cardiovascular events and mortality. We investigated the incidence of MEA and its associations with race and life-course socioeconomic position, as well as gender differences. METHODS: This prospective cohort study included 11 76…

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