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Peer-Reviewed Publication
Skeletal Radiol2026;55(6):1321-1327.June 1, 2026Journal Article

Clinical impact of adopting an AI-driven opportunistic bone health screening software using routine X-ray.

Catriona Aileen Syme1, Melanie Lopes1, Alexander Bilbily1,2, Mark D Cicero3,4,5
116 Bit Inc., 20 Bay Street, 11Th Floor, Toronto, ON, M5J 2N8, Canada.
2Sunnybrook Health Sciences, University of Toronto, Toronto, ON, Canada.
316 Bit Inc., 20 Bay Street, 11Th Floor, Toronto, ON, M5J 2N8, Canada. mark@16Bit.ai.
4True North Imaging, Toronto, ON, Canada. mark@16Bit.ai.
5Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada. mark@16Bit.ai.

Abstract

OBJECTIVES: To evaluate the clinical impact of an artificial intelligence device, Rho, that opportunistically screens X-rays for low bone mineral density (BMD; DXA T-score < -1). MATERIALS AND METHODS: Over 13 months, Rho analyzed X-rays from patients ≥ 50 years at a large independent health facility. Radiologists could opt to include Rho-flagged findings in their X-ray reports. DXAs that occurre…

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