Health AI Central
Peer-Reviewed Publication
Adv Sci (Weinh)2026;13(12):e22532.February 1, 2026Journal Article

Modulation of Network Plasticity Opens Novel Therapeutic Possibilities in Cancer, Diabetes, and Neurodegeneration.

Márk Kerestély1, István Narozsny1, Levente Szarka1, Daniel V Veres1,2, Peter Csermely1, Dávid Keresztes1
1Department of Molecular Biology, Semmelweis University, Budapest, Hungary.
2Turbine Simulated Cell Technologies, Budapest, Hungary.
PubMed PMC DOI PDF

Abstract

Cellular plasticity is crucially important in cancer-induced cell reprogramming, as well as in regeneration therapies in diabetes, Alzheimer's, and Parkinson's diseases. Protein-protein interaction, signaling, and gene regulatory networks are increasingly used to describe plasticity-induced cellular adaptation in disease progression. This review delineates how network analysis of cell plasticity l…

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