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Peer-Reviewed Publication
J Affect Disord2026;400120972.May 1, 2026Journal Article

Health-related quality of life and economic burden associated with likely and diagnosed generalized anxiety disorder among the US general adult population.

Phong Duong1, Ramin Mojtabai2, Erin Ferries3, Susan J Suponcic4, Kyla Finlayson5, Vicky W Li6, Nemin Chen7, Martine C Maculaitis8, Daniel R Karlin9
1Mind Medicine Inc., One World Trade Center Suite 8500, New York, NY, 10007, USA. Electronic address: pduong@mindmed.co.
2Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, LA, 70112, USA. Electronic address: rmojtabai@tulane.edu.
3Mind Medicine Inc., One World Trade Center Suite 8500, New York, NY, 10007, USA. Electronic address: eferries@mindmed.co.
4Value & Access Advisors, LLC, 1325 Snell Isle Blvd NE Unit 702, St Petersburg, FL, 33704, USA. Electronic address: susan.suponcic@valueandaccessadvisorsllc.com.
5Oracle Life Sciences, 2300 Oracle Way, Austin, TX, 78741, USA. Electronic address: kyla.finlayson@oracle.com.
6Oracle Life Sciences, 2300 Oracle Way, Austin, TX, 78741, USA. Electronic address: vicky.l.li@oracle.com.
7Oracle Life Sciences, 2300 Oracle Way, Austin, TX, 78741, USA. Electronic address: nemin.chen@oracle.com.
8Oracle Life Sciences, 2300 Oracle Way, Austin, TX, 78741, USA. Electronic address: martine.maculaitis@oracle.com.
9Mind Medicine Inc., One World Trade Center Suite 8500, New York, NY, 10007, USA. Electronic address: dkarlin@mindmed.co.

Abstract

BACKGROUND: Generalized anxiety disorder (GAD) remains widely underdiagnosed. The impact of GAD on adults who are likely to have GAD but are undiagnosed is not well understood. This study compared health-related quality of life (HRQoL) and economic burden among US adults with likely GAD, diagnosed GAD, and no GAD. METHODS: A retrospective, cross-sectional observational study was conducted using d…

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