Peer-Reviewed Publication
Sensors (Basel)2025;26(1)December 19, 2025Journal Article

Leveraging Central Sleep Apnea Events to Validate the Measurement of Lung Volume Changes Using Thoracic Bio-Impedance.

Martine A W Knoops-Borm1,2, Rik Vullings1, Hartmut Schneider2,3,4, , Sebastiaan Overeem1,5
1Department of Electrical Engineering, Eindhoven University of Technology, 5612 AP Eindhoven, The Netherlands.
2Onera Health, 5617 BD Eindhoven, The Netherlands.
3American Sleep Clinic, 60389 Frankfurt, Germany.
4Department of Pulmonary and Critical Care Medicine, Johns Hopkins Bayview Medical Campus, Johns Hopkins University, Baltimore, MD 21218, USA.
5Kempenhaeghe Centre for Sleep Medicine, 5591 VE Heeze, The Netherlands.

Abstract

Sleep disordered breathing can cause serious health issues, yet current diagnostic methods are cumbersome and prone to error. Thoracic electrical bio-impedance (BioZ) is a promising alternative, but it remains unclear whether the measured BioZ variations reflect lung volume changes. We leverage linear reductions in lung volume during central sleep apnea (CSA) events to assess whether BioZ measurem…

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