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Peer-Reviewed Publication
Cureus2026;18(1):e100818.January 1, 2026Journal Article

Quieting "Food Noise": How GLP-1s and Mindfulness Rewire the Default Mode Network (DMN) and Reward Circuits.

Geoff Cook1,2
1Nutrition, Noom, Princeton, USA.
2Nutrition, Friedman School of Nutrition, Tufts University, Boston, USA.
PubMed PMC DOI PDF

Abstract

This narrative review synthesizes evidence identified through targeted searches of PubMed, Scopus, and Web of Science (2010-2025), with a focused selection of human and mechanistic studies examining GLP-1 receptor agonists (GLP-1s), food cue reactivity, prospective cognition, mindfulness-based interventions, and neural network dynamics relevant to 'food noise' and the default mode network (DMN). F…

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