Peer-Reviewed Publication
JAMIA Open2026;9(1):ooaf176.February 1, 2026Journal Article
Comparing the effectiveness of a medication knowledge base product as designed with real-world hospital implementations using the Leapfrog Group's Computerized Physician Order Entry (CPOE/EHR) Evaluation Tool.
Zoe Co1,2, Howard R Strasberg3, Bruce R Hanway3, Dean F Sittig4,5, David C Classen6
1Department of Learning Health Sciences, University of Michigan Medical School, Ann Arbor, MI 48104, United States.
2Department of General Internal Medicine, Brigham and Women's Hospital, Boston, MA 02120, United States.
3Clinical Effectiveness, Wolters Kluwer Health, Indianapolis, IN 46240, United States.
4Department of Clinical and Health Informatics, McWilliams School of Biomedical Informatics, University of Texas Health Science Center at Houston, Houston, TX 77030, United States.
5Informatics Review LLC, Lake Oswego, OR 97034, United States.
6Division of Epidemiology, University of Utah School of Medicine, Salt Lake City, UT 84132, United States.
Abstract
OBJECTIVES: We sought to compare and analyze the performance of a medication knowledge base (MKB) vendor's (Medi-Span) fully enabled, factory settings product to operational implementations in hospitals using the Leapfrog Group's Computerized Physician Order Entry (CPOE)/electronic health record (EHR) Evaluation Tool.
MATERIALS AND METHODS: We randomly selected a hospital that used the MKB vendor…
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