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Peer-Reviewed Publication
J Perinatol2026January 5, 2026Journal Article

Skin InteGrity in extreme preterms research NETwork (SIGNET) - improving skin care for the most immature infants.

Deanne August1,2,3, Sabrina de Souza4, Vita Boyar5, Amy Curran6, Amy A Hobson7, Miki Konishi8, Gillion Noreiks9, Kylie Pussell10, Hannah Skelton11, Matthew A Rysavy12, Karen Walker13,14, Marty Visscher15, Pranav R Jani11,16
1Neonatology, Royal Brisbane and Women's Hospital, Brisbane, QLD, Australia. Deanne.August@health.qld.gov.
2Nursing, and Midwifery, Griffith University, Brisbane, QLD, Australia. Deanne.August@health.qld.gov.
3Nursing, Midwifery and Social Work, University of Queensland, Brisbane, QLD, Australia. Deanne.August@health.qld.gov.
4Nursing, Midwifery and Social Work, University of Queensland, Brisbane, QLD, Australia.
5Division Neonatology, K. Hovnanian Children's Hospital, Jersey Shore University Medical Center, Hackensack Meridian Health, Neptune, NJ, USA.
6Neonatology, Townsville University Hospital, Townsville, Australia.
7Department of Pediatrics, Division of Neonatology, University of Iowa, Iowa City, USA.
8Dokkyo Medical University, Tochigi, Japan.
9Neonatology, Royal Brisbane and Women's Hospital, Brisbane, QLD, Australia.
10Miracle Babies Foundation, Sydney, Australia.
11Department of Neonatology, Westmead Hospital, Westmead, NSW, Australia.
12Department of Pediatrics and Institute for Clinical Research and Learning Healthcare, McGovern Medical School, UTHealth Houston, Houston, TX, USA.
13Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia.
14Council of International Neonatal Nurses, Yardley, PA, USA.
15Colleges of Pharmacy and Medicine, University of Cincinnati, Cincinnati, OH, USA.
16The Reproduction and Perinatal Centre, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia.

Abstract

Increased survival of preterm infants born <28 weeks' gestation brings new challenges for healthcare teams and families, particularly in the absence of high-quality, population-specific evidence to guide optimal skin care. Skin integrity is critical for preventing infection, reducing pain, and minimizing fluid loss. However, variations in care, delivery models, geographic settings, and clinician e…

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