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Peer-Reviewed Publication
Adv Ther2026;43(2):710-728.February 1, 2026Journal Article

Challenges in Evaluating Clinical Remission in Severe Asthma: Insights from the Mayo Clinic.

Kaiser Lim1, Arijita Deb2, Thomas Corbridge3, Lydia Lee2, Judy Kelloway4, Safak Simsek5, Mithun Manoharan5, Hannah Barman5, Tyler Wagner5
1Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN, USA.
2Global Real-World Evidence and Health Outcomes Research, GSK, Upper Providence, PA, USA.
3Medical Affairs, GSK, 410 Blackwell Street, Durham, NC, 27701, USA. thomas.x.corbridge@gsk.com.
4Medical Affairs, GSK, 410 Blackwell Street, Durham, NC, 27701, USA.
5Nference, Cambridge, MA, USA.

Abstract

INTRODUCTION: Clinical remission (CR) is an ambitious and achievable treatment goal for many patients with severe asthma. This study evaluated real-life care of patients in the U.S. using CR criteria defined by the American Thoracic Society; American College of Allergy, Asthma, and Immunology; and American Academy of Allergy, Asthma & Immunology. METHODS: This retrospective cohort study (GSK ID:…

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