Peer-Reviewed Publication
Med Image Anal2026;109103890.March 1, 2026Journal Article

PISCO: Self-supervised k-space regularization for improved neural implicit k-space representations of dynamic MRI.

Veronika Spieker1, Hannah Eichhorn2, Wenqi Huang3, Jonathan K Stelter4, Tabita Catalan5, Rickmer F Braren6, Daniel Rueckert7, Francisco Sahli Costabal8, Kerstin Hammernik3, Dimitrios C Karampinos9, Claudia Prieto10, Julia A Schnabel11
1Institute of Machine Learning in Biomedical Imaging, Helmholtz Munich, Munich, Germany; School of Computation, Information and Technology, Technical University of Munich (TUM), Munich, Germany; Millenium Institute for Intelligent Healthcare Engineering, Santiago, Chile. Electronic address: v.spieker@tum.de.
2Institute of Machine Learning in Biomedical Imaging, Helmholtz Munich, Munich, Germany; School of Computation, Information and Technology, Technical University of Munich (TUM), Munich, Germany.
3School of Computation, Information and Technology, Technical University of Munich (TUM), Munich, Germany.
4School of Medicine and Health, Klinikum rechts der Isar, Technical University of Munich (TUM), Munich, Germany.
5Millenium Institute for Intelligent Healthcare Engineering, Santiago, Chile; School of Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile.
6School of Medicine and Health, Klinikum rechts der Isar, Technical University of Munich (TUM), Munich, Germany; Department of Diagnostic and Interventional Radiology and Department of Nuclear Medicine, University Medical Center Hamburg Eppendorf, Hamburg, Germany.
7School of Computation, Information and Technology, Technical University of Munich (TUM), Munich, Germany; School of Medicine and Health, Klinikum rechts der Isar, Technical University of Munich (TUM), Munich, Germany; Department of Computing, Imperial College London, London, UK; Munich Center for Machine Learning (MCML), Munich, Germany.
8Millenium Institute for Intelligent Healthcare Engineering, Santiago, Chile; School of Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile; Institute for Biological and Medical Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile.
9School of Medicine and Health, Klinikum rechts der Isar, Technical University of Munich (TUM), Munich, Germany; Laboratory of Magnetic Resonance Imaging Systems and Methods, Ecole Polytechnique Federale de Lausanne (EPFL), Lausanne, Switzerland; Center for Biomedical Imaging (CIBM), Lausanne, Switzerland.
10Millenium Institute for Intelligent Healthcare Engineering, Santiago, Chile; School of Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile; School of Biomedical Imaging and Imaging Sciences, Kings College London, London, UK.
11Institute of Machine Learning in Biomedical Imaging, Helmholtz Munich, Munich, Germany; School of Computation, Information and Technology, Technical University of Munich (TUM), Munich, Germany; School of Medicine and Health, Klinikum rechts der Isar, Technical University of Munich (TUM), Munich, Germany; Munich Center for Machine Learning (MCML), Munich, Germany; School of Biomedical Imaging and Imaging Sciences, Kings College London, London, UK.

Abstract

Neural implicit k-space representations (NIK) have shown promising results for dynamic magnetic resonance imaging (MRI) at high temporal resolutions. Yet, reducing acquisition time, and thereby available training data, results in severe performance drops due to overfitting. To address this, we introduce a novel self-supervised k-space loss function LPISCO, applicable for regularization of NIK-base…

Create a free account to keep reading

Free members get 10 full research views every month across publications, clinical trials, FDA clearances, adverse events, and NIH grants. No credit card required.

Want unlimited research access? See Pro plans

Data Accuracy Notice: Research intelligence on Health AI Central is aggregated from public sources (PubMed, ClinicalTrials.gov, FDA, NIH, CMS, and others) and refreshed nightly. Classifications and derived metrics are produced by automated methods described in our Methodology. We recommend verifying critical data points against the primary sources before making decisions.