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Peer-Reviewed Publication
J Appl Physiol (1985)2026;140(1):1-19.January 1, 2026Journal Article

Big bones mean big muscles: an MRI-based dataset of muscle-bone-body size relationships across 70 human muscles of the upper limb, trunk, and lower limb.

Lara Riem1, Megan Pinette1, Olivia DuCharme1, Valeria Pabon1,2, Jacob Morris1, Ashley Coggins1, Liza Harold1, Kathryn Eve Costanzo1, Matthew Cousins1, Raina Hein1, Matt Rhodes1, Eline Lievens3, Rajvi Shah4, Xue Feng1,2, Savannah Benusa1, Tim Breeding1, Michael D Nelson4, Wim Derave3, Silvia S Blemker1,2
1Springbok Analytics, Charlottesville, Virginia, United States.
2Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, United States.
3Department of Movement & Sports Sciences, Ghent University, Ghent, Belgium.
4Department of Kinesiology, University of Texas at Arlington, Arlington, Texas, United States.

Abstract

Body sizes and shapes vary widely, even among healthy adults, resulting in diverse muscle sizes, strengths, and performance capacities. This study developed an artificially intelligent (AI) algorithm to segment individual muscles and bones from whole body MRI scans of 102 healthy adults (49 males, 53 females) aged 18-50 yr, generating three-dimensional (3-D) segmentations of 70 muscles and 13 bone…

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