Health AI Central
Peer-Reviewed Publication
NPJ Syst Biol Appl2025;11(1):132.November 21, 2025Journal Article

MarkerPredict: predicting clinically relevant predictive biomarkers with machine learning.

Daniel V Veres1,2, Peter Csermely1, Klára Schulc3,4
1Department of Molecular Biology, Semmelweis University, Budapest, Hungary.
2Turbine Ltd, Budapest, Hungary.
3Department of Molecular Biology, Semmelweis University, Budapest, Hungary. schulc.klara@semmelweis.hu.
4Division of Oncology, Department of Internal Medicine and Oncology, Semmelweis University, Budapest, Hungary. schulc.klara@semmelweis.hu.
PubMed PMC DOI PDF

Abstract

Precision oncology relies on predictive biomarkers for selecting targeted cancer therapies. Network-based properties of proteins, together with structural features such as intrinsic disorder, are likely to shape their potential as biomarkers. We therefore designed a hypothesis-generating framework that integrates network motifs and protein disorder to explore their contribution to predictive bioma…

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