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Peer-Reviewed Publication
Am Heart J Plus2025;60100657.December 1, 2025Journal Article

Association of the triglyceride-glucose index with all-cause and cause-specific mortality in patients with comorbid hypertension and diabetes: A population-based cohort study.

Jiahao Zou1, Song Lu1, Kaishen Cao2, Ruihong He1, Xia Feng1, Shuang Yang1, Wen Liu1, Haochen Liu1, Zhichao Wang3, Ruichun Liao1, Jin Chen1, Xiaoting Jiang1, Xiaoping Peng1,2,4,3,5
1Department of Cardiology, The First Affiliated Hospital, Jiangxi Medicai College, Nanchang University, Nanchang, Jiangxi, China.
2Jiangxi Medicai College, Nanchang University, Nanchang, Jiangxi, China.
3Jiangxi Key Laboratory of Neurological Diseases, Department of Cardiology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China.
4Jiangxi Hypertension Research Institute, Nanchang, Jiangxi, China.
5Academician Workstation of Cardiovascular Innovative Materials, Nanchang, Jiangxi, China.

Abstract

STUDY OBJECTIVE: Although the triglyceride-glucose (TyG) index has been shown to be an independent risk factor for either hypertension or diabetes, its association with the coexistence of both conditions remains unclear. This study aimed to evaluate the association between the TyG index and all-cause and cause-specific mortality among patients with comorbid hypertension and diabetes. DESIGN: To e…

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