Peer-Reviewed Publication
JMIR Form Res2025;9e71831.October 30, 2025Journal Article

Leveraging Artificial Intelligence for Clinical Study Matching: Key Threads for Interweaving Data Science and Implementation Science.

Andrew James Goodwin1, Sara Ann Armstrong2, David Ptak3, Kenneth Catchpole4, Jihad S Obeid5, Paul M Heider5
1Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, Medical University of South Carolina, Suite 816 CSB, MSC 630, 96 Jonathan Lucas St., Charleston, SC, 29425, United States, 1 8437924728.
2Department of Medicine, Medical University of South Carolina, Charleston, SC, United States.
3Biomedical Informatics Center, Medical University of South Carolina, Charleston, SC, United States.
4Department of Anesthesia and Perioperative Medicine, Medical University of South Carolina, Charleston, SC, United States.
5Department of Public Health Sciences, Medical University of South Carolina, Charleston, SC, United States.

Abstract

Artificial intelligence holds the potential to enhance the efficiency of clinical research. Yet, like all innovations, its impact is dependent upon target user uptake and adoption. As efforts to leverage artificial intelligence for clinical trial screening become more widespread, it is imperative that implementation science principles be incorporated in both the design and roll-out of user-facing…

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