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Peer-Reviewed Publication
Sci Rep2025;15(1):35069.October 8, 2025Journal Article

Assessing the risk of recurrence in early-stage breast cancer through H&E stained whole slide images.

Geongyu Lee1, Joonho Lee1, Tae-Yeong Kwak1, Sun Woo Kim1, Youngmee Kwon2, Chungyeul Kim3, Hyeyoon Chang4
1Research Team, Deep Bio Inc., Seoul, Seoul, 08380, Republic of Korea.
2Department of Pathology, National Cancer Center, Goyang, Goyang, 10408, Republic of Korea.
3Department of Pathology, Korea University Guro Hospital, Seoul, Seoul, 08380, Republic of Korea. idea1@korea.ac.kr.
4Department of Pathology, Deep Bio Inc., Seoul, Seoul, 08380, Republic of Korea. hychang@deepbio.co.kr.

Abstract

Accurate prediction of the likelihood of recurrence is important in the selection of postoperative treatment for patients with early-stage breast cancer. In this study, we investigated whether deep learning algorithms can predict patients' risk of recurrence by analyzing the pathology images of their cancer histology. We analyzed 125 hematoxylin and eosin-stained whole slide images (WSIs) from 125…

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