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Peer-Reviewed Publication
Chest2026;170(1):238-249.July 1, 2026Journal Article

Positive Airway Pressure Therapy and Health Care Resource Use in Patients With OSA and Comorbid Insomnia.

Kate V Cole1, Anita S Malik2, Peter A Cistulli3, Kimberly L Sterling2, Atul Malhotra4, Naomi Alpert2, Jean-Louis Pépin5,
1Resmed Science Center, San Diego, CA. Electronic address: kate.cole@resmed.com.
2Resmed Science Center, San Diego, CA.
3Charles Perkins Centre, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia; Royal North Shore Hospital, Sydney, NSW, Australia.
4University of California, San Diego, La Jolla, CA.
5University Grenoble-Alps and HP2 Laboratory, INSERM, La Tronche, France.

Abstract

BACKGROUND: Insomnia and OSA, together known as comorbid insomnia and OSA (COMISA), are highly prevalent sleep disorders, each of which has the potential to impair treatment efficacy for the other. RESEARCH QUESTION: Is adherence to positive airway pressure (PAP) therapy, the first-line treatment for OSA, associated with reduced health care resource use in patients with COMISA? STUDY DESIGN AND…

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