Peer-Reviewed Publication
Stroke2025;56(10):2966-2975.October 1, 2025Journal Article

Accuracy of Large Language Models to Identify Stroke Subtypes Within Unstructured Electronic Health Record Data.

Dylan Owens1, Danh Q Nguyen1, Michael Dohopolski2,3, Justin F Rousseau4,5, Eric D Peterson1, Ann Marie Navar1
1Department of Medicine (D.O., D.Q.N., E.D.P., A.M.N.), UT Southwestern Medical Center, Dallas, TX.
2Department of Radiation Oncology (M.D.), UT Southwestern Medical Center, Dallas, TX.
3Medical Artificial Intelligence and Automation Lab (M.D.), UT Southwestern Medical Center, Dallas, TX.
4Biostatistics and Clinical Informatics Section, Department of Neurology (J.F.R.), UT Southwestern Medical Center, Dallas, TX.
5Peter O'Donnell Jr. Brain Institute (J.F.R.), UT Southwestern Medical Center, Dallas, TX.

Abstract

BACKGROUND: While International Classification of Diseases, Tenth Revision codes suffice for identifying stroke events in surveillance, accurately classifying stroke types and subtypes using electronic health records remains challenging due to limitations in structured data. This often necessitates manual review of clinical documentation. This study evaluated whether a large language model, Genera…

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