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Peer-Reviewed Publication
J Med Imaging (Bellingham)2025;12(4):044502.July 1, 2025Journal Article

Deep-learning-based washout classification for decision support in contrast-enhanced ultrasound examinations of the liver.

Hannah Strohm1, Sven Rothlübbers1, Jürgen Jenne1, Dirk-André Clevert2, Thomas Fischer3, Niklas Hitschrich4, Bernhard Mumm4, Paul Spiesecke3, Matthias Günther1,5
1Fraunhofer Institute for Digital Medicine MEVIS, Bremen, Germany.
2Ludwig-Maximilians-University Munich, Department of Radiology, Munich, Germany.
3Charité-Universitätsmedizin Berlin, Interdisciplinary Ultrasound Center, Department of Radiology, Berlin, Germany.
4TOMTEC Imaging Systems, Unterschleißheim, Germany.
5University of Bremen, Bremen, Germany.

Abstract

PURPOSE: Contrast-enhanced ultrasound (CEUS) is a reliable tool to diagnose focal liver lesions, which appear ambiguous in normal B-mode ultrasound. However, interpretation of the dynamic contrast sequences can be challenging, hindering the widespread application of CEUS. We investigate the use of a deep-learning-based image classifier for determining the diagnosis-relevant feature washout from CE…

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