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Peer-Reviewed Publication
JMIR AI2025;4e69149.June 19, 2025Journal Article

Digital Phenotyping for Detecting Depression Severity in a Large Payor-Provider System: Retrospective Study of Speech and Language Model Performance.

Bradley Karlin1,2, Doug Henry1, Ryan Anderson1, Salvatore Cieri1, Michael Aratow3, Elizabeth Shriberg3, Michelle Hoy3
1Highmark Health, 120 Fifth Avenue, Fifth Avenue Place, Pittsburgh, PA, 15222-3099, United States, 1 (412) 544-7000.
2Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States.
3Ellipsis Health, 548 Market Street, PMB 49051, San Francisco, CA, 94104-5401, United States, 1 800-410-5383.

Abstract

BACKGROUND: There is considerable need to improve and increase the detection and measurement of depression. The use of speech as a digital biomarker of depression represents a considerable opportunity for transforming and accelerating depression identification and treatment; however, research to date has primarily consisted of small-sample feasibility or pilot studies incorporating highly controll…

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