Comparison of Flow Dynamics After Left Atrial Appendage Occlusion With the Watchman FLX Versus Amulet Devices: Implications for Device-Related Thrombosis.

Ahmad Bshennaty¹, Brennan J Vogl¹, Ghasaq Saleh², Alessandra Maria Bavo³, Agata Sularz², Karam Ghazal-Aswad², Anders Dahl Kramer⁴, Yuheng Jia⁵, Matthieu De Beule³, Jens Erik Nielsen-Kudsk⁴, Ole De Backer⁵, Mohamad Alkhouli², Hoda Hatoum^1,6

¹Department of Biomedical Engineering, Michigan Technological University, Houghton, Michigan, USA.

²Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA.

³FEops, Gent, Belgium.

⁴Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark.

⁵Department of Cardiology, Copenhagen University Hospital, Copenhagen, Denmark.

⁶Health Research Institute, Center of Biocomputing and Digital Health and Institute of Computing and cybersystems, Michigan Technological University, Houghton, Michigan, USA.

PubMed DOI

Abstract

BACKGROUND: This study aims to assess how Watchman FLX (Boston Scientific) and Amplatzer Amulet (Abbott) devices for left atrial appendage occlusion (LAAO) impact the flow dynamics in the LA and the risk of device-related thrombosis (DRT). METHODS: Flow simulations were carried out for 12 AF patients before and after undergoing LAAO. Six patients had Watchman FLX while the other six had Amulet de…

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Mentioned Companies

FEops
affiliation

Other Funding

This study was funded by the American Heart Association award #24CDA1269661.

MeSH Terms

Humans0Atrial Appendage*Atrial Fibrillation*Cardiac Catheterization*Thrombosis*Aged0Treatment Outcome0Male0Models, Cardiovascular0Female0Time Factors0Atrial Function, Left*Risk Factors0Blood Flow Velocity0Middle Aged0Computer Simulation0Prosthesis Design0Septal Occluder Device*Aged, 80 and over0Patient-Specific Modeling0Hemodynamics*

Article Info

PMID: 40556123
DOI: 10.1002/ccd.31710
Received: May 5, 2025
Accepted: June 17, 2025

How to Cite

Bshennaty A et al. Comparison of Flow Dynamics After Left Atrial Appendage Occlusion With the Watchman FLX Versus Amulet Devices: Implications for Device-Related Thrombosis. Catheter Cardiovasc Interv2025;106(4):2084-2092. doi:10.1002/ccd.31710

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