Benchmarking test-retest variability in microperimetry for intermediate age-related macular degeneration using MP-3 and MAIA.

Jakob Schweighofer¹, Klaudia Birner², Hamza Mohamed³, Johannes Schrittwieser³, Hrvoje Bogunovic⁴, Gregor S Reiter², Ursula Schmidt-Erfurth⁵

¹Department of Ophthalmology and Optometry, Medical University of Vienna, Vienna, Austria.

²Department of Ophthalmology and Optometry, Medical University of Vienna, Vienna, Austria; Laboratory for Ophthalmic Image Analysis, Department of Ophthalmology and Optometry, Medical University of Vienna, Vienna, Austria.

³Laboratory for Ophthalmic Image Analysis, Department of Ophthalmology and Optometry, Medical University of Vienna, Vienna, Austria.

⁴Center for Medical Data Science (Institute of Artificial Intelligence), Medical University of Vienna, Vienna, Austria.

⁵Department of Ophthalmology and Optometry, Medical University of Vienna, Vienna, Austria; Laboratory for Ophthalmic Image Analysis, Department of Ophthalmology and Optometry, Medical University of Vienna, Vienna, Austria. Electronic address: ursula.schmidt-erfurth@meduniwien.ac.at.

PubMed DOI

Abstract

OBJECTIVE: Microperimetry (MP) has emerged as a clinical functional endpoint in nonexudative age-related macular degeneration (AMD). In this study, we aim to provide reference values for test-retest outcomes on two MP devices in intermediate AMD (iAMD). DESIGN: Prospective, cross-sectional study. PARTICIPANTS: 3 600 stimuli from 20 eyes in 20 subjects. METHODS: Patients diagnosed with iAMD unde…

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