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Peer-Reviewed Publication
J Med Imaging (Bellingham)2025;12(3):034502.May 1, 2025Journal Article

Classifying chronic obstructive pulmonary disease status using computed tomography imaging and convolutional neural networks: comparison of model input image types and training data severity.

Sara Rezvanjou1, Amir Moslemi2, Samuel Peterson3, Wan-Cheng Tan4, James C Hogg4, Jean Bourbeau5, Joseph M Reinhardt6, Miranda Kirby1,4
1Toronto Metropolitan University, Department of Physics, Toronto, Ontario, Canada.
2Sunnybrook Research Institute, Toronto, Ontario, Canada.
3VIDA Diagnostics, Coralville, Iowa, United States.
4University of British Columbia, Centre for Heart Lung Innovation, Vancouver, British Columbia, Canada.
5Montreal Chest Institute of the Royal Victoria Hospital, Montreal, Quebec, Canada.
6University of Iowa, Roy J. Carver Department of Biomedical Engineering, Iowa City, United States.

Abstract

PURPOSE: Convolutional neural network (CNN)-based models using computed tomography images can classify chronic obstructive pulmonary disease (COPD) with high performance, but various input image types have been investigated, and it is unclear what image types are optimal. We propose a 2D airway-optimized topological multiplanar reformat (tMPR) input image and compare its performance with establish…

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