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Peer-Reviewed Publication
Hum Genomics2025;19(1):61.May 24, 2025Journal Article

Causal impact of genetically-determined fish and fish oil intake on epigenetic age acceleration and related serum markers.

Paul Fabian1, Gil Blander1, Renee Deehan1, Ali Torkamani2,3, Bartek Nogal4,5
1InsideTracker, One Broadway, 14 th 10 Fl, Cambridge, MA, 02142, USA.
2The Scripps Translational Science Institute, The Scripps Research Institute, La Jolla, CA, 92037, USA.
3Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, 92037, USA.
4InsideTracker, One Broadway, 14 th 10 Fl, Cambridge, MA, 02142, USA. bnogal@scripps.edu.
5Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, 92037, USA. bnogal@scripps.edu.

Abstract

BACKGROUND: The interplay between diet and healthspan is a topic of great interest in biomedical research. Toward this end, consumption of marine omega-3 fatty acids is of particular significance, as reports suggest that diets focused on seafood can prolong the disease-free portion of the human lifespan. Fish consumption has also been linked to reduced biological aging as measured by epigenetic cl…

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