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Crit Care Med2025;53(7):e1355-e1364.July 1, 2025Journal Article

Risk Analytics Clinical Decision Support Decreases Duration of Vasoactive Infusions Following Pediatric Cardiac Surgery: A Multicenter Before and After Clinical Trial.

Avihu Z Gazit1, Craig Futterman2, Dimitar Baronov3, Adam Tomczak3, Michael P Goldsmith4, Victor B Talisa5, Vinay M Nadkarni6, Peter C Laussen7, Joshua W Salvin8
1Department of Critical Care Medicine, Division of Pediatric Cardiac Critical Care Medicine, University of Pittsburgh, Children's Hospital Pittsburgh, Pittsburgh, PA.
2Division of Cardiac Critical Care Medicine, George Washington University, Children's National Hospital, Washington, DC.
3Etiometry, Inc, Boston, MA.
4Department of Anesthesiology and Critical Care Medicine, Division of Cardiac Critical Care Medicine, University of Pennsylvania Perelman School of Medicine, Children's Hospital of Philadelphia, Philadelphia, PA.
5Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA.
6Department of Anesthesiology, Critical Care, and Pediatrics, University of Pennsylvania Perelman School of Medicine, Children's Hospital of Philadelphia, Philadelphia, PA.
7Harvard Medical School, Boston Children's Hospital, Boston, MA.
8Department of Cardiology, Division of Cardiovascular Critical Care Medicine, Harvard Medical School, Boston Children's Hospital, Boston, MA.
PubMed PMC DOI PDF

Abstract

OBJECTIVES: Our primary objective was to quantify the effect of a clinical decision support system (CDSS) informed by inadequate delivery of oxygen index (ID o2 ), an algorithm that estimates the probability of inadequate oxygen delivery on inotropes and vasoactive infusions (IVAI) postoperatively. DESIGN: Multicenter before-and-after study conducted between June 01, 2020, and December 31, 2022.…

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