Assessment of sestamibi CZT-SPECT reconstructed using deep-learning-based virtual attenuation correction maps according to coronary artery territory and with comparison to rubidium-PET.

Telma Sprauel¹, Laetitia Imbert², Kaya Doyeux³, Mathieu Perrin¹, Marine Claudin¹, Véronique Roch¹, Matthieu Doyen⁴, Nathaniel Roth⁵, Yechiel Lamash⁵, Renata Chequer⁶, François Rouzet⁶, Fabien Hyafil⁷, Pierre-Yves Marie⁸

¹Université de Lorraine, Department of Nuclear Medicine and Nancyclotep Imaging Platform, CHRU Nancy, F-54000, Nancy, France.

²Université de Lorraine, Department of Nuclear Medicine and Nancyclotep Imaging Platform, CHRU Nancy, F-54000, Nancy, France; Université de Lorraine, IADI, INSERM U1254, F-54000, Nancy, France.

³Department of Nuclear Medicine, Bichat University Hospital, Assistance Publique-Hopitaux de Paris (AP-HP), F-75000, Paris, France.

⁴Université de Lorraine, IADI, INSERM U1254, F-54000, Nancy, France.

⁵Spectrum Dynamics Medical, Caesarea, Israel.

⁶Department of Nuclear Medicine, Bichat University Hospital, Assistance Publique-Hopitaux de Paris (AP-HP), F-75000, Paris, France; Université Paris Cité, INSERM U 1148, F-75000, Paris, France.

⁷Department of Nuclear Medicine, DMU IMAGINA, European Hospital Georges-Pompidou, Assistance Publique-Hopitaux de Paris (AP-HP), F-75015, Paris, France; INSERM U 970, University Paris-City, F-75015, Paris, France.

⁸Université de Lorraine, Department of Nuclear Medicine and Nancyclotep Imaging Platform, CHRU Nancy, F-54000, Nancy, France; Université de Lorraine, IADI, INSERM U1254, F-54000, Nancy, France. Electronic address: py.marie@chru-nancy.fr.

PubMed DOI

Abstract

BACKGROUND: Attenuation artifacts affect the analysis of single-photon emission computed tomography (SPECT) myocardial perfusion imaging, especially in the right coronary artery (RCA) territory, although computed tomography (CT)-based attenuation corrections minimize this issue. This study aims to assess stress-rest [99mTc]sestamibi cadmium zinc telluride (CZT)-SPECT reconstructed using deep-learn…

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Mentioned Companies

Spectrum Dynamics Medical
affiliation

MeSH Terms

Aged0Female0Humans0Male0Middle Aged0Artifacts0Cadmium0Coronary Artery Disease*Coronary Vessels*Deep Learning*Image Processing, Computer-Assisted*Myocardial Perfusion Imaging0Positron-Emission Tomography*Radiopharmaceuticals0Rubidium Radioisotopes0Technetium Tc 99m Sestamibi*Tellurium0Tomography, Emission-Computed, Single-Photon*Zinc0

Keywords

Attenuation correctionCZT-cameraDeep learningMyocardial perfusion imagingRubidium-PETSestamibi-SPECT

Article Info

PMID: 40258438
DOI: 10.1016/j.nuclcard.2025.102226
Received: January 9, 2025
Accepted: April 13, 2025

How to Cite

Sprauel T et al. Assessment of sestamibi CZT-SPECT reconstructed using deep-learning-based virtual attenuation correction maps according to coronary artery territory and with comparison to rubidium-PET. J Nucl Cardiol2025;49102226. doi:10.1016/j.nuclcard.2025.102226

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