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Peer-Reviewed Publication
Cancer Treat Res Commun2025;43100784.January 1, 2025Journal Article

The symptom burden of women with a known risk of breast cancer receiving risk reducing medication.

Meagan S Whisenant1, Jessica Treviño Jones2, Anneliese O Gonzalez2, Therese Bartholomew Bevers3, Kelly Brassil4, Darcy A Ponce5, Sharvari Kamat6, Emily Solis6, Ann Maliackal6, Hannah Warlick6, Amie Walters6, Chloe Denham2, Loretta A Williams7
1Department of Behavioral Science, Division of Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, CPB3.3001, Houston, Texas 77030, USA. Electronic address: mswhisenant@mdanderson.org.
2Division of Hematology/Oncology, McGovern Medical School, The University of Texas Health Science Center at Houston, 6431 Fannin, MSB 1.150, Houston, Texas 77030, USA.
3Department of Clinical Cancer Prevention, Division of Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, 1155 Pressler Street, CPB6.3500, Houston, Texas 77030, USA.
4Pack Health, a Quest Diagnostics Company, 110 12(th) Street North, Birmingham, Alabama, 35203, USA.
5Department of Behavioral Science, Division of Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, CPB3.3001, Houston, Texas 77030, USA.
6Department of Research, Cizik School of Nursing, The University of Texas Health Science Center at Houston, 6901 Bertner Avenue, Houston, Texas 77030, USA.
7Department of Symptom Research, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 1450, Houston, Texas 77030, USA.

Abstract

BACKGROUND: For the estimated 10 million women in the United States who meet the high-risk criteria for breast cancer, evidence-based interventions may reduce the risk of breast cancer by 50-65 %. Even with substantial evidence supporting preventive medication for risk reduction, there is significant lack of uptake and adherence. The purpose of this study was to characterize the experience of wome…

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