Neural Mechanisms of Poststroke Urinary Incontinence: Results From an fMRI Study.

Evgeniy I Kreydin^1,2,3, Aidin Abedi^4,2, Luis Morales^1,3, Stefania Montero^1,3,5, Priya Kohli^3,6, Nhi Ha^3,6, David Chapman¹, Armita Abedi⁷, David Ginsberg^1,3, Kay Jann⁸, Richard L Harvey^9,10, Charles Y Liu^1,4,2,3

¹Department of Urology (E.I.K., L.M., S.M., D.C., D.G., C.Y.L.), Keck School of Medicine of the University of Southern California, Los Angeles.

²USC Neurorestoration Center (E.I.K., Aidin Abedi, C.Y.L.), University of Southern California, Los Angeles.

³Rancho Los Amigos National Rehabilitation Center, Downey, CA (E.I.K., L.M., S.M., P.K., N.H., D.G., C.Y.L.).

⁴Department of Neurological Surgery (Aidin Abedi, C.Y.L.), Keck School of Medicine of the University of Southern California, Los Angeles.

⁵Department of Surgery, Anschutz Medical Campus, University of Colorado School of Medicine, Aurora (S.M.).

⁶Keck School of Medicine of the University of Southern California, Los Angeles (P.K., N.H.).

⁷School of Medicine, Zanjan University of Medical Sciences, Iran (Armita Abedi).

⁸Mark and Mary Stevens Neuroimaging and Informatics Institute (K.J.), University of Southern California, Los Angeles.

⁹Shirley Ryan AbilityLab, Chicago, IL (R.L.H.).

¹⁰Feinberg School of Medicine, Northwestern University, Chicago, IL (R.L.H.).

PubMed DOI

Abstract

BACKGROUND: Urinary incontinence after a stroke significantly affects patient outcomes and quality of life. It is commonly associated with uninhibited detrusor contractions, but the underlying neural mechanisms remain poorly understood. This study aimed to explore the brain activity patterns associated with volitional and involuntary bladder contractions in stroke survivors. METHODS: This cohort…

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