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Peer-Reviewed Publication
Lancet Digit Health2025;7(4):e255-e263.April 1, 2025Journal Article

Snapshot artificial intelligence-determination of ejection fraction from a single frame still image: a multi-institutional, retrospective model development and validation study.

Jeffrey G Malins1, D M Anisuzzaman1, John I Jackson1, Eunjung Lee1, Jwan A Naser1, Behrouz Rostami1, Jared G Bird1, Dan Spiegelstein2, Talia Amar2, Jae K Oh1, Patricia A Pellikka1, Jeremy J Thaden1, Francisco Lopez-Jimenez1, Sorin V Pislaru1, Paul A Friedman1, Garvan C Kane1, Zachi I Attia3
1Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
2UltraSight, Rehovot, Israel.
3Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA. Electronic address: attia.itzhak@mayo.edu.

Abstract

BACKGROUND: Artificial intelligence (AI) is poised to transform point-of-care practice by providing rapid snapshots of cardiac functioning. Although previous AI models have been developed to estimate left ventricular ejection fraction (LVEF), they have typically used video clips as input, which can be computationally intensive. In the current study, we aimed to develop an LVEF estimation model tha…

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