Development and validation of a HPLC-DAD method for determining the content of tryptamines in methanolic extracts of fruiting bodies of mushrooms belonging to species of the Psilocybe genus.

Juan Pablo Yasmo Perez¹, Carolina Chegwin Angarita², Omar David Saldarriaga Ochoa³, Sergio Andrés Urrego Restrepo⁴

¹Grupo de Investigación Química de Hongos Macromicetos. Universidad Nacional de Colombia, Sede Bogotá. Departamento de Química, Colombia. Electronic address: jpyasmop@unal.edu.co.

²Grupo de Investigación Química de Hongos Macromicetos. Universidad Nacional de Colombia, Sede Bogotá. Departamento de Química, Colombia. Electronic address: cchegwina@unal.edu.co.

³AITIA BIOTECH S.A.S, Colombia. Electronic address: innovacion@aitia.bio.

⁴AITIA BIOTECH S.A.S, Colombia. Electronic address: gerencia@aitia.bio.

PubMed DOI

Abstract

This study presents the development and validation of a high-performance liquid chromatography method with diode array detection (HPLC-DAD) for determining the content of tryptamines in methanolic extracts of dried fruiting bodies of mushrooms belonging to species of the Psilocybe genus. The objective is to initiate the assessment of tryptamine content in fungi marketed as Psilocybes in Colombia,…

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