Peer-Reviewed Publication
Physiol Meas2025;13(2)February 25, 2025Journal Article

Detection of occult hemorrhage using multivariate non-invasive technologies: a porcine study.

Navid Rashedi1, Ethan K Murphy1, Samuel B Klein2,3, Alexandra Hamlin1, Justin E Anderson2, Joseph M Minichiello2, Alexander L Lindqwister2, Karen L Moodie2, Zachary J Wanken3, Jackson T Read2, Victor A Borza1, Jonathan T Elliott1,3, Ryan J Halter1,3, Vikrant S Vaze1, Norman A Paradis2,3
1Thayer School of Engineering, Dartmouth College, 15 Thayer Dr, Hanover, NH 03755, United States of America.
2Geisel School of Medicine, Dartmouth College, 1 Rope Ferry Rd, Hanover, NH 03755, United States of America.
3Dartmouth-Hitchcock Medical Center (DHMC), Lebanon, NH 03756, United States of America.

Abstract

Objective.Occult hemorrhage (OH) can emerge subtly post-trauma, especially when internal bleeding is not yet severe enough to result in noticeable hemodynamic changes or shock. Despite normal appearances of traditional vital signs like heart rate (HR) and blood pressure (BP), clinically significant OH may be present, posing a critical diagnostic challenge. Early detection of OH, before vital signs…

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