Dielectric blood coagulometry to evaluate coagulation activity in patients prescribed factor Xa inhibitors undergoing elective surgery: A prospective observational study.

Aya Takemoto¹, Nobuyo Kondo¹, Akiko Kitajo¹, Hiroto Yamamoto¹, Yudai Yamamoto¹, Koji Higashino², Tokujiro Uchida³

¹Department of Anesthesiology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, Japan.

²Arkray Marketing Inc., 1-20-20 Yotsuya, Shinjuku-ku, Tokyo 160-0004, Japan.

³Department of Anesthesiology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, Japan. Electronic address: uchida.mane@tmd.ac.jp.

PubMed DOI

Abstract

BACKGROUND: Dielectric blood coagulometry (DBCM) is a coagulation test based on dielectric permittivity. We recently developed a new cartridge to evaluate the anticoagulation effect of factor Xa inhibitors and investigated the usefulness of this system in the clinical setting. Here, we evaluate the relationship among the coagulation time measured by DBCM, plasma concentrations of factor Xa inhibit…

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