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Peer-Reviewed Publication
J Glaucoma2025;34(5):404-414.May 1, 2025Journal Article

Performance of Optic Disc Optical Coherence Tomography Normative Database in a Large, Diverse, Real-World Cohort.

Rithambara Ramachandran1, Ming-Chen Lu1, Leslie M Niziol1, Maria A Woodward1,2, Angela R Elam1,2, Leroy Johnson3, Martha Kershaw4, David C Musch1,5,2, Amanda Bicket1, Denise John1, Sarah Dougherty Wood1, Amy Zhang1, Jason Zhang1, Joan O'Brien6, Paula Anne Newman-Casey1,2
1Departments of Ophthalmology and Visual Sciences.
2Institute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor.
3Hamilton Community Health Network, Federally Qualified Health Center, Flint.
4Hope Clinic, community health center, Ypsilanti, MI.
5Epidemiology.
6Department of Ophthalmology, Scheie Eye Institute, University of Pennsylvania, PA.

Abstract

PRÉCIS: Current optical coherence tomography normative sample data may not represent the diversity of human optic nerve anatomy needed to accurately classify all individuals with true glaucomatous optic neuropathy. PURPOSE: To compare optic nerve head (ONH) measurements between published values from an optical coherence tomography (OCT) normative database and a larger, more diverse cohort of heal…

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