Development of a Body of Knowledge for the Clinical Bioinformatician: Perspectives from the Association for Molecular Pathology's Clinical Bioinformatician Body of Knowledge Steering Committee.

Somak Roy¹, Amber M Fussell², Danielle Jordan², Sabah Kadri³, Annette Leon⁴, Ryan J Schmidt⁵, Robyn L Temple-Smolkin², Jason D Merker⁶

¹The AMP Clinical Bioinformatician Body of Knowledge Steering Committee of the Informatics Subdivision, Association for Molecular Pathology, Rockville, Maryland; Cincinnati Children's Hospital Medical Center and University of Cincinnati, Cincinnati, Ohio. Electronic address: somak.roy@cchmc.org.

²The Association for Molecular Pathology, Rockville, Maryland.

³The AMP Clinical Bioinformatician Body of Knowledge Steering Committee of the Informatics Subdivision, Association for Molecular Pathology, Rockville, Maryland; AbbVie, North Chicago, Illinois; Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.

⁴The AMP Clinical Bioinformatician Body of Knowledge Steering Committee of the Informatics Subdivision, Association for Molecular Pathology, Rockville, Maryland; Fabric Genomics, Oakland, California.

⁵The AMP Clinical Bioinformatician Body of Knowledge Steering Committee of the Informatics Subdivision, Association for Molecular Pathology, Rockville, Maryland; Children's Hospital Los Angeles, Los Angeles, California; Keck School of Medicine of USC, Los Angeles, California.

⁶The AMP Clinical Bioinformatician Body of Knowledge Steering Committee of the Informatics Subdivision, Association for Molecular Pathology, Rockville, Maryland; Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, North Carolina; Departments of Pathology and Laboratory Medicine and Genetics, University of North Carolina School of Medicine, Chapel Hill, North Carolina.

PubMed PMC DOI PDF

Abstract

The use of next-generation sequencing and other high-throughput technologies in the clinical molecular diagnostics laboratory requires the application of bioinformatics pipelines and other computational tools to analyze, visualize, and store these clinical data. Clinical bioinformaticians, individuals with the skills to develop, validate, and deploy these tools in a clinical setting, are needed to…

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