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Peer-Reviewed Publication
J Neurointerv Surg2025;18(1):149-154.December 17, 2025Journal Article

CT perfusion for lesion-symptom mapping in large vessel occlusion ischemic stroke.

James William Garrard1,2, Ain Neuhaus3, Davide Carone4,2, Olivier Joly4, Armin Zarrintan5, Alejandro A Rabinstein6, Thien Huynh6, George Harston4,2, Waleed Brinjikji5, David F Kallmes5
1Brainomix, Oxford, UK jgarrard@brainomix.com.
2Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
3Acute Stroke Programme, Department of Medicine, University of Oxford Radcliffe, Oxford, UK.
4Brainomix, Oxford, UK.
5Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
6Mayo Clinic, Rochester, Minnesota, USA.
PubMed DOI

Abstract

BACKGROUND: Identifying eloquent regions associated with poor outcomes based on CT perfusion (CTP) may help inform personalized decisions on selection for endovascular therapy (EVT) in patients with large vessel occlusion (LVO) ischemic stroke. This study aimed to characterize the relationship between CTP-defined hypoperfusion and National Institutes of Health Stroke Scale (NIHSS) subitem deficits…

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