Peer-Reviewed Publication
Vaccines (Basel)2024;12(11)November 1, 2024Journal Article
Multi-Epitopic Peptide Vaccine Against Newcastle Disease Virus: Molecular Dynamics Simulation and Experimental Validation.
Muhammad Tariq Zeb1,2, Elise Dumont3,4, Muhammad Tahir Khan5,6,7, Aroosa Shehzadi5, Irshad Ahmad1
1Department of Molecular Biology and Genetics, Institute of Basic Medical Sciences, Khyber Medical University, Phase-V, Hayatabad Peshawar, Peshawar 25100, Pakistan.
2Genomic Laboratory, Veterinary Research Institute, Bacha Khan Chowk, Charsadda Road, Peshawar 25100, Pakistan.
3Institut de Chimie de Nice, Université Côte d'Azur, CNRS, UMR 7272, 06108 Nice, France.
4Institut Universitaire de France, 5 Rue Descartes, 75005 Paris, France.
5Institute of Molecular Biology & Biotechnology (IMBB), The University of Lahore, KM Defence Road, Lahore 54000, Pakistan.
6State Key Laboratory of Respiratory Disease, Guangzhou Key Laboratory of Tuberculosis Research, Department of Clinical Laboratory, Guangzhou Chest Hospital, Institute of Tuberculosis, Guangzhou Medical University, Guangzhou 510180, China.
7Qihe Laboratory, Qishui Guang East, Qibin District, Hebi 458030, China.
Abstract
BACKGROUND: Newcastle disease virus (NDV) is a highly contagious and economically devastating pathogen affecting poultry worldwide, leading to significant losses in the poultry industry. Despite existing vaccines, outbreaks continue to occur, highlighting the need for more effective vaccination strategies. Developing a multi-epitopic peptide vaccine offers a promising approach to enhance protectio…
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