Artificial intelligence algorithms enhance urine cytology reporting confidence in postoperative follow-up for upper urinary tract urothelial carcinoma.

Cheng-Che Chen^1,2,3, Tsung-Han Yen¹, Jian-Ri Li^1,3, Chih-Jung Chen^4,5,6, Chi-Shun Yang⁶, Jing-Yi Lai⁶, Shu-Jiuan Lin⁶, Cheng-Hung Yeh^7,8, Shih-Wen Hsu^7,8, Ming-Yu Lin^7,8, Tien-Jen Liu^7,8, Chuan Shu Chen^9,10,11

¹Department of Urology, Taichung Veterans General Hospital, Taichung, Taiwan.

²BioAnalytical Chemistry and Nanobiomedicine Laboratory, Department of Biochemical Science and Technology, National Taiwan University, Taipei, Taiwan.

³Department of Medicine and Nursing, Hungkuang University, Taichung, Taiwan.

⁴Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan ROC.

⁵Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan ROC.

⁶Department of Pathology and Laboratory Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.

⁷AlxMed Inc., Taipei, 111045, Taiwan.

⁸AIxMed, Inc., Santa Clara, CA, USA.

⁹Department of Urology, Taichung Veterans General Hospital, Taichung, Taiwan. r2060d@gmail.com.

¹⁰Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan ROC. r2060d@gmail.com.

¹¹Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan ROC. r2060d@gmail.com.

PubMed PMC DOI PDF

Abstract

PURPOSE: In Taiwan, the incidence of urothelial carcinoma of the upper urinary tract (UTUC) is high and intravesical recurrence is approximately 22%-47%. Thus, postoperative cystoscopy and urine cytology follow-up, which require experienced cytologists, are needed. The AIxURO system aligns with The Paris System (TPS) guidelines for reporting urinary cytology. This study assessed the benefit of ear…

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